Type 2 diabetes is a lifelong (chronic) disease that
develops when the pancreas cannot produce enough insulin or the
body is unable to use it. In many people, the body first becomes
resistant to insulin and then eventually loses the ability to
produce it.
Insulin is a hormone that allows sugar (glucose) to enter cells,
where it is used for energy. It also helps the body store extra
sugar in muscle, fat, and liver cells. The stored sugar can be
released later and used for energy when needed. When the body
does not have enough insulin or cannot use it properly, the
blood sugar level rises above what is healthy. Very high blood
sugar levels can lead to loss of consciousness (coma) and death.
Uncontrolled diabetes over time can lead to complications, such
as damage to the heart, blood vessels, eyes, kidneys, and
nerves.
In the past, type 2 diabetes was considered an adult disease.
Type 1 diabetes was associated with children. However, the
number of children being diagnosed with type 2 diabetes is
increasing. In some areas, up to 45% of the children diagnosed
with diabetes have type 2. 1
The major factors that increase a child's risk for developing
type 2 diabetes are being overweight, not physically active, and
having a family history of the disease.
What causes it?
The cause is not known, but experts believe a family history of
diabetes, being overweight, and lack of exercise contribute to
the disease. Other risk factors include:
* Being female.
* Being an African-American, Hispanic, Native American,
Asian-American, or Pacific Islander.
* Having a mother who had diabetes that developed during
pregnancy (gestational diabetes).
During the early teen years, when children are growing rapidly,
hormone changes reduce the body's ability to use insulin. The
pancreas produces more insulin to try to overcome the
resistance. When the pancreas cannot produce enough insulin to
meet the body's needs, blood sugar levels rise above a healthy
range, and diabetes develops.
What are the symptoms?
Most children with type 2 diabetes do not have symptoms when the
disease is diagnosed. Diabetes is usually discovered when the
child sees a health professional for another reason. If symptoms
are present, they are usually mild—slight increases in frequency
of urination and in thirst and a slight weight loss.
Some children have very high blood sugar levels when the disease
is discovered. A child with very high blood sugar can become
confused, sleepy, or unconscious, and will need to be taken to
the emergency room and hospitalized.
How is it diagnosed?
A simple blood test is usually all that is needed to diagnose
diabetes. If it is unclear whether your child has type 1 or type
2, other blood tests may be done.
Most children are diagnosed with type 2 diabetes when they have
a blood or urine test for some other reason. A health
professional also may test your child for diabetes if he or she
is overweight, gets little physical activity, or has other risk
factors for the disease. In addition, your child may be tested
if he or she has certain medical problems that also can occur in
people with diabetes, such as high blood pressure, high
cholesterol, irregular menstrual periods or polycystic ovary
syndrome, a skin condition called acanthosis nigricans, or
persistent infections.